Not for best results. Thrush resides in the dark, warm, moist crevices that are deep in the horse's frog. Spraying Banixx™ onto the feet just doesn't reach those deepest places, so this method will not treat the root of the thrush infection. Banixx™ needs to make good contact with the bacterial infection to aid in its removal. This is one reason why we recommend using a medicine boot to treat thrush.